Devic's neuromyelitis optica and Schilder's myelinoclastic diffuse sclerosis.
نویسنده
چکیده
An adult patient developed both Devic's neuromyelitis optica and Schilder's myelinoclastic diffuse sclerosis, suggesting that these entities represent rare topographical and aggressive variants within the spectrum of multiple sclerosis.
منابع مشابه
Neuromyelitis optica (Devic's syndrome): no association with the primary mitochondrial DNA mutations found in Leber hereditary optic neuropathy.
Devic's neuromyelitis optica is a rare syndrome characterised by the combination of acute or subacute optic neuritis and transverse myelitis, in some cases considered to be a variant of multiple sclerosis. Mutations of mitochondrial DNA (mtDNA) associated with Leber hereditary optic neuropathy (LHON) have been identified in some patients with multiple sclerosis in whom optic neuritis is a promi...
متن کاملClinical, CSF, and MRI findings in Devic's neuromyelitis optica.
OBJECTIVES Since Devic's original description of neuromyelitis optica in 1894 there has been much debate regarding its aetiology. A specific cause has been identified in a minority of cases but in most the question has arisen whether or not Devic's neuromyelitis optica is a variant of multiple sclerosis. This study was undertaken to help clarify this issue. METHODS Neuromyelitis optica was de...
متن کاملInflammatory myelinoclastic diffuse sclerosis (Schilder's disease): neuroradiologic findings.
Controversy has surrounded the rare clinicopathologic entity of inflammatory myelinoclastic diffuse sclerosis (IMDS) since the seminal description of Schilder in 1912 [1]. Since that time several distinct myelinoclastic and dysmyelinating conditions have been grouped under this eponym. To this newly described demyelinating disease, the author planted the seeds of an enduring controversy by incl...
متن کاملNeuromyelitis Optica in Children: A Rare Entity
Neuromyelitis optica (also known as Devic's disease or Devic's syndrome) is an uncommon disorder in pediatric age group, and is characterized by acute or subacute optic neuritis and transverse myelitis. Here we report an 11- year- old female child with relapsing Neuromyelitis optica (NMO) confirmed by positive NMO- IgG antibody and had clinical recovery with high dose methyl prednisolone t...
متن کاملThe spectrum of neuromyelitis optica.
Neuromyelitis optica (also known as Devic's disease) is an idiopathic, severe, demyelinating disease of the central nervous system that preferentially affects the optic nerve and spinal cord. Neuromyelitis optica has a worldwide distribution, poor prognosis, and has long been thought of as a variant of multiple sclerosis; however, clinical, laboratory, immunological, and pathological characteri...
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ورودعنوان ژورنال:
- Journal of neurology, neurosurgery, and psychiatry
دوره 56 12 شماره
صفحات -
تاریخ انتشار 1992